Venom Allergies
Venom allergies are an allergic reaction to an insect bite or sting. The severity of insect venom allergy varies from person to person but can range from mild to life-threatening, and can get more serious over time.
What are venom allergies?
Venom allergies are an immune response to the venom in an insect sting, most commonly from a bee or a wasp. Venom allergies can affect the skin, gut, breathing, and circulation.
Approximately 0.3% to 7.5% of the general population experience immediate systemic reactions to insect stings, which can vary in severity from localised and mild, to life-threatening.
Patients with venom allergies are seen in our purpose-built Allergy centre, designed to give patients expert care and advanced treatment options.
More information
The symptoms of venom allergy vary depending on the severity of the reaction.
Localised reaction:
The site of the sting may become swollen, red, itchy, and uncomfortable, with swelling less than 10cm in diameter. A localised reaction will often go down within 24 hours.
Mild systemic reaction:
Swelling and hives appear in areas other than the site of the sting. This type of reaction can last for a few days.
Severe allergic reaction (anaphylaxis):
This type of reaction is life-threatening and should always be treated as a medical emergency requiring immediate treatment.
Symptoms of anaphylaxis include:
a rapid, weak pulse
sudden difficulty breathing
swelling of the face, lips, tongue and throat
difficulty swallowing or speaking
large hives or a rash on the body
flushed, red skin
abdominal cramps, nausea and vomiting
dizziness and fainting
collapse and unconsciousness
Anaphylactic death resulting from an insect sting can occur within 15 to 20 minutes of being stung without treatment.
Insect venom allergies can get worse over time, as the immune system may respond more strongly if exposed to the same allergen again. A mild reaction to a sting may be followed by a more severe or life-threatening reaction to subsequent stings.
If you have a history of allergic reactions to insect stings, we recommend consulting one of our allergists at the Allergy centre to confirm your diagnosis and explore options to help manage and reduce the risk of future reactions.
Venom allergies are caused by an immune system overreaction to proteins in insect venom. The immune system mistakenly identifies the venom proteins as harmful and then releases chemicals like histamine, which cause the symptoms of venom allergy.
The process leading to this overreaction (sensitisation) happens over time, not usually when the person is first stung. After the first sting, the immune system becomes more sensitive to the proteins in the venom and reactions to subsequent stings can be more severe.
People who get stung more often are more likely to develop a venom allergy (for example, beekeepers, gardeners, and pest controllers). Patients who have venom allergy and also have an underlying cardiac condition or mastocytosis are at higher risk of having a severe reaction.
Our allergists will review your symptoms and medical history at an initial consultation in our specialist Allergy centre. They will also use skin prick tests and blood tests to confirm a diagnosis of venom allergy.
The best way to prevent a venom allergy from happening is to limit exposure to insects and reduce the risk of being stung:
avoid eating outside, especially on the ground, or in spaces with lots of plants and trees
wear closed shoes whenever possible and avoid walking barefoot on grass
stay calm around insects – rather than swatting them, slowly move away, gently brush them off, or wait still for them to leave
check food and drink before each bite or sip to make sure an insect hasn’t landed
avoid using sweet-smelling fragrances and toiletries, as these can attract bees
keep car and house windows closed to keep insects out
wear clothes that cover the arms and legs, and avoid wearing bright-coloured or floral clothing as these can attract insects
address any insect problems, hives, or nests in and around your home
The main complication of insect venom allergy is anaphylaxis. This type of reaction is life-threatening and should always be treated as a medical emergency requiring immediate treatment.
Other, more rare, complications include:
serum sickness – a reaction that occurs days or weeks after exposure and can cause fever, rash and joint pain
vasculitis – inflammation of blood vessels
neurological complications – nerve or brain inflammation.
Mild and localised sting reactions can be self-treated by:
scraping (not pulling) the stinger off the skin to limit the amount of venom released
applying a cold compress, or an ice pack, on the affected area
taking an antihistamine such as cetirizine, loratadine, or fexofenadine for a few days
applying a topical antihistamine preparation, hydrocortisone cream, or calamine lotion
taking over-the-counter painkillers such as paracetamol or ibuprofen to help ease discomfort
If you have a more severe allergy, our allergists will offer specific advice on treatments to help manage the risk of future reactions based on your allergy.
Treatment options include:
anti-allergic treatment – antihistamines, corticosteroids, or adrenaline, such as an adrenaline pen
venom desensitisation therapy – a series of injections is given over a number of years that work to change the natural reaction to the venom and reduce symptoms of severe reactions
At Welbeck, our allergists are experts in their field and are dedicated to providing world-class care to every patient.
With access to colleagues across other specialties, our consultants are also able to refer within the Welbeck ecosystem if required to ensure you receive the treatment you need as quickly as possible, all under one roof.
All appointments, testing, treatment, and follow-up appointments take place within our state-of-the-art facilities, enabling us to deliver accurate diagnostics and advanced treatments.
Your health is important to us, so we strive to offer same-day appointments whenever possible.
Our consultants are recognised by the major health insurance companies. If you have private health insurance, your treatment at Welbeck can begin once you have obtained authorisation. We also provide care to self-paying patients. Learn more about the different payment options at Welbeck.
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Frequently asked questions
A normal reaction to a sting involves redness, a small amount of swelling, and localised pain at the site of the sting. An allergic reaction involves swelling beyond the sting area and may also affect the gut, breathing and circulation. If you’re unsure if you have a venom allergy, our allergists will be able to help with a diagnosis.
It’s not common for venom allergies to go away on their own, and over time, the body may become more sensitised to venom, making reactions worse.
The risk of developing anaphylaxis is greater if you’ve had a severe reaction to a sting in the past. It’s important to see an allergist to confirm diagnosis and discuss treatment options.
Venom desensitisation is a very effective treatment for venom allergy. Once the maximum dose is reached, most people have no reaction to stings, and some have a mild reaction (skin only, for example). Most people can stop carrying adrenaline pens once the maximum dose is reached.


