LLETZ treatment for cervical cell changes
Large loop excision of the transformation zone (LLETZ) is a common procedure used to remove abnormal cells from the cervix. It’s usually recommended when high-grade cell changes have been identified during cervical screening and colposcopy.
What is LLETZ treatment?
LLETZ stands for large loop excision of the transformation zone. It’s a treatment used to remove abnormal cells from the cervix, which is the opening to the womb at the top of the vagina.
The procedure removes the area of cervical tissue where abnormal cells are most likely to develop – the transformation zone. Treating abnormal cells early helps prevent cervical cancer from developing in the future.
LLETZ is most often recommended after:
abnormal cervical screening (smear test) results
a colposcopy showing high-grade changes
biopsy results confirming high-grade cervical intraepithelial neoplasia (CIN)
persistent abnormal cervical cells that haven’t returned to normal
Most abnormal cervical cell changes are not cancer. However, some types can become cancerous over time if they’re not monitored or treated.
At Welbeck, LLETZ procedures are carried out by specialist consultant gynaecologists in our Women’s Health centre using advanced equipment and evidence-based techniques. We understand that needing treatment after abnormal cervical screening results can feel worrying, and our specialists are here to guide you through every stage of your care.
More information
LLETZ is usually performed as an outpatient procedure under local anaesthetic, which means you can go home on the same day. The treatment itself normally takes around 10 to 20 minutes.
Before the procedure begins, your consultant will explain each step and answer any questions you may have.
During the procedure:
You’ll lie on an examination couch, similar to during cervical screening.
A speculum is gently inserted into the vagina so the cervix can be seen clearly.
The cervix is examined using a medical microscope called a colposcope.
A local anaesthetic is then injected into the cervix to numb the area and reduce discomfort.
A thin, heated wire loop is used to remove the abnormal area of tissue.
The tissue sample is sent to a laboratory for further testing.
Bleeding is controlled using a small ball electrode or a special solution.
Most people remain awake throughout the procedure. You may feel some pressure, mild cramping, or discomfort similar to period pain, but severe pain is uncommon.
After a short recovery period, you’ll usually be able to return home the same day.
LLETZ is considered to be a very safe and effective procedure. Serious complications are uncommon, especially when the treatment is carried out by an experienced specialist.
Possible risks and side effects include:
temporary watery or brown vaginal discharge
light bleeding or spotting for up to 4 weeks
mild cramping or period-like pain
infection
heavier bleeding in rare cases
narrowing of the cervix in rare cases
a small increased risk of premature birth in future pregnancies, particularly if large amounts of cervical tissue are removed
Most people recover without complications. Your consultant will explain any risks that apply specifically to you before treatment.
You should seek medical advice if you develop:
heavy bleeding that soaks pads
severe abdominal pain
a high temperature
unpleasant-smelling vaginal discharge
symptoms that worsen rather than improve
Your consultant will give you personalised instructions before your procedure. In most cases, preparation for LLETZ is straightforward.
You may be advised to:
avoid scheduling the procedure during a heavy period
eat and drink normally before the appointment if you’re having a local anaesthetic
bring a sanitary pad to wear afterwards, as light bleeding is common
wear comfortable clothing
arrange for someone to accompany you home if you feel anxious or unwell afterwards
It’s important to tell your consultant if you:
are pregnant or think you may be pregnant
take blood-thinning medication
have allergies to medicines or anaesthetics
have an infection or unusual vaginal symptoms before your appointment
You may wish to take simple pain relief, such as paracetamol or ibuprofen, before attending your appointment if your consultant advises this.
days. However, your cervix will need time to heal properly.
It’s normal to experience:
mild cramping for a few hours or days
light bleeding or spotting
dark brown or watery vaginal discharge for up to 4 weeks
To reduce the risk of infection and support healing, your consultant will usually advise you to avoid the following for around 4 weeks, or until bleeding has stopped completely:
penetrative sex
using tampons
swimming
heavy exercise or strenuous activity
You can usually shower and bathe as normal.
Most people can drive themselves home after the procedure if they feel comfortable. However, if you feel anxious, dizzy, or uncomfortable, you may prefer to arrange for someone to accompany you.
Over-the-counter pain relief, such as paracetamol or ibuprofen, can help manage any mild discomfort. Antibiotics are not routinely needed unless there are signs of infection.
You’ll usually receive your laboratory results within a few days. Your consultant will explain whether any further monitoring or treatment is needed. Most people will be invited for follow-up cervical screening around 6 months after treatment to confirm the abnormal cells have been successfully removed.
Please contact our Women’s Health centre for up-to-date pricing information and payment options.
To book a LLETZ procedure, you must be referred by either your GP or a specialist gynaecologist following a consultation with them. Self-referrals are not accepted for this treatment.
If you would like to schedule a consultation with a specialist, please get in touch to make an appointment. Your health is important to us, so we strive to offer same-day appointments whenever possible.
Our consultants are recognised by the major health insurance companies. If you have private health insurance, your treatment at Welbeck can begin once you have obtained authorisation. We also provide care to self-paying patients. Learn more about the different payment options at Welbeck.
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Frequently asked questions
LLETZ treatment doesn’t usually affect your ability to become pregnant. Most people go on to have healthy pregnancies after treatment. In some cases, removing larger areas of cervical tissue may slightly increase the risk of premature birth, but your consultant will discuss this with you if relevant.
Most people find LLETZ uncomfortable rather than painful. The local anaesthetic numbs the cervix, although you may still feel pressure, mild cramping, or sensations similar to period pain during the procedure.
LLETZ is highly effective at removing abnormal cervical cells. In most cases, one treatment successfully removes the affected tissue completely. Follow-up cervical screening is still important to monitor your cervical health.
Yes, abnormal cells can return, although this is uncommon. Attending your follow-up cervical screening appointments is important, as it helps identify any future changes early so they can be monitored or treated promptly.

